FLOXIUM TABLETS                  Back to Products

Floxium contains Levofloxacin, a chiral fluorinated carboxyquinolone antimicrobial agent with activity against a broad spectrum of gram-positive and gram-negative bacteria and intracellular pathogens.

 

COMPOSITION

Floxium: Each film coated, scored tablet contains 500mg Levofloxacin.

 

INDICATIONS

Floxium is indicated for the treatment of infections caused by susceptible microorganisms in the following:

 

  • Acute maxillary sinusitis.

  • Acute bacterial Exacerbation of Chronic Bronchitis.

  • Community-acquired pneumonia.

  • Nosocomial pneumonia

  • Complicated skin and skin structure infections.

  • Uncomplicated skin and skin structure infections.

  • Complicated urinary tract infections.

  • Acute pyelonephritis.

  • Uncomplicated urinary tract infections.

  • Chronic Bacteria Prostatitis

  • Intra Abdominal Infections

  • Gynecological Infections

  • Bone Infections (acute & chronic)

  • Enteric Infections

  • Surgical Prophylaxis

 

DOSAGE AND ADMINISTRATION

The recommended daily dose of Floxium in patients with normal renal function is as listed below in the indications:

 

Acute bacteria exacerbation of chronic bronchitis : 500mg once daily for 7 days.

Community Acquired Pneumonia : 500mg once daily for 7-14 days.

Nosocomial Pneumonia : 750mg once daily for 7-14days.

Acute Maxillary Sinusitis : 500mg once daily for 10-14 days.

Urinary Tract Infection (Non-Uncomplicated) : 250mg once daily for 3 days.

Urinary Tract Infection (Complicated) : 250mg once daily for 10 days.

Acute Pyelonephritis : 250mg once daily for 10 days.

Salmonella Typhi & Paratyphi : 500mg once daily for 10-14 days.

Complicated Skin and Skin Structure Infection: 750mg once daily for 7-14 days.

Uncomplicated Skin and Skin Structure Infection : 500mg once daily for 7-10 days.

Chronic bacteria prostatitis : 500mg once daily for 28 days.

Bone infection : 500mg daily for 4-6 weeks.

Enteric Infection : 500mg daily for 10-14 days.

Anthrax : 500mg daily for 60 days.

Other infections, duration of therapy is 7-14 days.

In severe infection the above dosages could be increased to 500mg twice a day.

In patients with renal insufficiency (creatinine clearance <50ml/min), the clearance of levofloxacin is substantially reduced and plasma half-life is prolonged, therefore dosage adjustment is required to avoid accumulation.

Floxium can be taken with or without food.

 

SIDE EFFECTS

Levofloxacin is generally well tolerated. Likely side effect includes nausea, vomiting, diarrhea, fungal overgrowth, insomnia, abdominal pain, flatulence, pruritus, dizziness, dyspepsia, rash, constipation, arthralgia, nervousness.

 

PRECAUTION

Its usage is not recommended in pregnancy, breast feeding and infants. Convulsion and toxic psychoses have been reported in patients receiving quinolones including levofloxacin. If these reactions occur in patients receiving Floxium, the drug should be discontinued and appropriate measures instituted.

As with other quinolones, levofloxacin should be used with caution in patients with a known CNS disorder that may predispose to seizures or lower the seizures threshold.

 

CONTRAINDICATIONS

Levofloxacin is contraindicated in persons with a history of hypersensitivity to levofloxacin, or any other quinolone antimicrobial agents.

 

PRESENTATION

Floxium Tablet 500mg, pack of 7’s

 


For more information, please contact productmanager@solidumpharma.com
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